重組人干擾素-γ, IFN-γ

貨號:

300-02

品牌:

Peprotech

規格:

20μg

概述

Immune Interferon, type II interferon, T cell interferon, MAF

研究領(lǐng)域:

細胞生物學(xué)

詳述

IFN-γ is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells.? IFN-γ receptors are present in most immune cells, which respond to IFN-γ signaling by increasing the surface expression of class I MHC proteins.? This promotes the presentation of antigen to T-helper (CD4+) cells.? IFN-γ signaling in antigen-presenting cells, and antigen-recognizing B and T lymphocytes, regulates the antigen-specific phases of the immune response.? Additionally, IFN-γ stimulates a number of lymphoid cell functions, including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils.? Human IFN-γ is species-specific and is biologically active only in human and primate cells.? Recombinant Human IFN-γ is a 16.8 kDa protein containing 144 amino acid residues.

氨基酸序列:

MQDPYVKEAE NLKKYFNAGH SDVADNGTLF LGILKNWKEE SDRKIMQSQI VSFYFKLFKN FKDDQSIQKS VETIKEDMNV KFFNSNKKKR DDFEKLTNYS VTDLNVQRKA IHELIQVMAE LSPAAKTGKR KRSQMLFQGR RASQ

來(lái)源:

E.coli

純度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Assay #1:?Determined by its ability to induce apoptosis in HeLa cells. The expected ED₅₀?for this effect is 5.0-10.0 ng/ml.
Assay #2:?The ED₅₀?determined by a cytotoxicity assay using HT-29 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 10⁷units/mg.

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交叉反應:

Monkey, Human, Mouse, Leech, Pig, Human + Bacteria, Mandarin Fish, Fish + Virus, N/A, Human + Mouse

儲存與安全

儲存:

2℃~8℃

關(guān)于我們

Wolcavi Biotech致力于干細胞免疫治療、分子生物學(xué) 、免疫學(xué)、體外診斷等相關(guān)領(lǐng)域的實(shí)驗需求產(chǎn)品開(kāi)發(fā)和銷(xiāo)售。主要產(chǎn)品有抗原抗體|無(wú)血清培養基|細胞培養耗材并代理銷(xiāo)售Abcam、Invitrogen(Gibco)、Roche、Sigma、R&D、Meridian等二十多家國外知名品牌。

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重組人干擾素-γ, IFN-γ