Recombinant Human IL-1α 重組人白細胞介素-1α

貨號:

200-01A

品牌:

Peprotech

規格:

20μg

概述

Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)重組人白細胞介素-1α,

研究領(lǐng)域:

腫瘤類(lèi)

細胞生物學(xué)

詳述

IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells.? Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties.? These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the release of prostaglandin and collagenase from synovial cells.? However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine.? Recombinant Human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.

氨基酸序列:

SAPFSFLSNV KYNFMRIIKY EFILNDALNQ SIIRANDQYL TAAALHNLDE AVKFDMGAYK SSKDDAKITV ILRISKTQLY VTAQDEDQPV LLKEMPEIPK TITGSETNLL FFWETHGTKN YFTSVAHPNL FIATKQDYWV CLAGGPPSIT DFQILENQA

來(lái)源:

E.coli

純度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

The?ED₅₀?as determined by the dose-dependent stimulation of murine D10S cells is ≤ 0.001 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁹units/mg.

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交叉反應:

Cow, Monkey, Mouse, Human, Frog, Pig

儲存與安全

儲存:

2℃~8℃

關(guān)于我們

Wolcavi Biotech致力于干細胞免疫治療、分子生物學(xué) 、免疫學(xué)、體外診斷等相關(guān)領(lǐng)域的實(shí)驗需求產(chǎn)品開(kāi)發(fā)和銷(xiāo)售。主要產(chǎn)品有抗原抗體|無(wú)血清培養基|細胞培養耗材并代理銷(xiāo)售Abcam、Invitrogen(Gibco)、Roche、Sigma、R&D、Meridian等二十多家國外知名品牌。

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Recombinant Human IL-1α 重組人白細胞介素-1α