Recombinant Human VEGF165

貨號:

100-20

品牌:

Peprotech

規格:

20μg

概述

Vascular Endothelial Growth Factor, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen, VEGF-A

研究領(lǐng)域:

細胞生物學(xué)

詳述

VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant Human VEGF₁₆₅?is a 38.2 kDa, disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

氨基酸序列:

APMAEGGGQN HHEVVKFMDV YQRSYCHPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCGGC CNDEGLECVP TEESNITMQI MRIKPHQGQH IGEMSFLQHN KCECRPKKDR ARQENPCGPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

來(lái)源:

E.coli

純度:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

生物活性:

Determined by the dose-dependent stimulation of the proliferation of human umbilical vein endothelial cells (HUVEC) using a concentration range of 1.0-8.0 ng/ml.

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交叉反應:

Cow, Guinea Pig, Hamster, Mouse, Pig, Rabbit, Rat, Sheep, Trout, Human, Chicken, Leech, Zebra Fish, Gelatin Microparticles, Rat + Chicken, Human + Mouse, Horse, Tunicate

儲存與安全

儲存:

2℃~8℃

關(guān)于我們

Wolcavi Biotech致力于干細胞免疫治療、分子生物學(xué) 、免疫學(xué)、體外診斷等相關(guān)領(lǐng)域的實(shí)驗需求產(chǎn)品開(kāi)發(fā)和銷(xiāo)售。主要產(chǎn)品有抗原抗體|無(wú)血清培養基|細胞培養耗材并代理銷(xiāo)售Abcam、Invitrogen(Gibco)、Roche、Sigma、R&D、Meridian等二十多家國外知名品牌。

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Recombinant Human VEGF165